Nephrotic and nephritic syndrome renal pathology by dr. A comparison between nephritic and nephrotic syndrome from professor hossam mowafy. Nephrotic syndrome vs nephritic syndrome explained nephritic. In all cases, injury to glomeruli is an essential feature. Although there may be overlap in clinical presentation, and some patients present with clinical features. In a nephrotic syndrome, a group of manifestations occur, such as protein in the urine, edema, low count of albumin in the blood, and lastly too much lipids or fats circulating in the blood. Nephrotic syndrome vs nephritic syndrome explained nephritic vs nephrotic.
Hematuria originates from compromised glomeruli, and is the most common and most common sign. Nephrotic syndrome vs nephritic syndrome explained. It can be caused by a variety of conditions including autoimmune, hereditary, and infectious diseases. This learning card provides an overview of nephritic syndrome. Development of nephrotic syndrome during treatment with mercurial diuretics. Other symptoms may include weight gain, feeling tired, and foamy urine. Mar 23, 2017 nephrotic syndrome vs nephritic syndrome. Mum fights with me and im sad membranous gn focal segmental glomerulosclerosis. The nephrotic syndrome is defined by a urinary protein level exceeding 3. Efforts to minimize treatment toxicity showed that prolonged treatment after an initial treatment for 23 months with glucocorticosteroids. Because nephritic syndrome is a syndrome and not a disease, the prognosis depends on the underlying cause. Glomerulonephritis including nephrotic and nephritic. As a nursing student, you must be familiar with nephrotic syndrome and acute glomerulonephritis along with how to care for patients who are experiencing these conditions. All glomerular diseases can progress to acute or chronic renal failure.
Ppt acute nephritic syndrome powerpoint presentation. Nps and pas have provided great feedback on pneumonia treatment and liver function tests. Nephrotic syndrome is a group of symptoms that, together, show that your kidneys are not working as well as they should. In a nephritic syndrome, all of these occur plus there. It contains different signs or indications of the nephritis which a diseases of the kidneys. Nonetheless, age should not be the only factor in defining the etiology of nephritic. Nephrotic syndrome is kidney disease with proteinuria. Causes of nephritic syndrome include postinfectious glomerulonephritis, iga nephropathy berger disease, thin basement membrane disease, and rapidly progressive glomerulonephritis. Nephrotic vs nephritic syndrome proteinuria, hematuria. Nephrotic syndrome 75% 15% manifestations 26, some adults 2.
This video will explain further on the two syndromes of kidney. However, some glomerular diseases especially the mpgn can present as nephrotic or nephritic. It can be caused nephritic syndrome knowledge for medical students and physicians. Nephrotic syndrome may appear as a primary idiopathic renal disease or occur in association with any of a number of systemic conditions and hereditary diseases. The most widespread of the theories explaining the pathogenesis of the nephrotic syndrome is the immunological theory. Nephrotic vs nephritic syndrome proteinuria, hematuria, casts. Nephrotic syndrome is characterized by large amounts of proteinuria 3. Difference between glomerulonephritis and nephrotic syndrome. But the fine line which makes them two separate disease entities is drawn across the degree of proteinuria, if the protein loss is higher than 3. By contrast, nephrotic syndrome is characterized by only proteins moving into the urine. First deciding between nephritic and nephrotic syndrome is a useful starting point for your differential diagnosis. Nephrotic syndrome with a nephritic component associated with.
Nephritic syndrome is a disease of kidney structure element glomeruli. Nephrotic syndrome poc nephritic syndrome edema hypoalbuminemia proteinuria hypercholesterolemia not essential characteristic htn mild edema oliguria azotemia high jvp dark urine any inflammation cause proteinuria then edema then hypovolemia then more hypoalbuminemia and hyperlipidemia mechanism 2 immunological disorder causing thickening. Symptoms symptoms of nephrotic syndrome immense proteinuria is usually a common finding in the nephrotic syndrome. Apr 01, 2015 in a nephrotic syndrome, a group of manifestations occur, such as protein in the urine, edema, low count of albumin in the blood, and lastly too much lipids or fats circulating in the blood. In nephritic syndrome, there is some proteinuria and edema, but its not nearly as severe as in nephrotic syndrome. Definitions of nephrotic syndrome jsn kdigo urine protein. Nephrotic syndrome is a collection of symptoms due to kidney damage. Proteinuria and nephrotic syndrome proteinuria and nephrotic syndrome hamid moradi m. Difference between nephrotic syndrome and nephritic syndrome. At the most basic level, remember that nephrotic syndrome involves the loss of a lot of protein, whereas nephritic syndrome involves the loss of a lot of blood. Ppt acute nephritic syndrome powerpoint presentation free. Find, read and cite all the research you need on researchgate.
Nephrotic syndrome versus nephritic syndrome both nephritis and nephrosis are among the bodys responses to injury or illness affecting the kidneys. Nephritic syndrome is also called glomerulonephritis. Nephritic syndrome is a condition involving haematuria, mild to moderate proteinuria typically less than 3. Difference between nephrotic and nephritic syndrome. Pdf acute glomerulonephritis mimicking nephrotic syndrome.
By contrast, nephrotic syndrome is characterized by only proteins proteinuria moving into the urine. Nephritic syndrome knowledge for medical students and. Nephrotic syndrome versus nephritic syndrome current. Pig arm poststreptococcal gn iga nephropathy goodpastures syndrome alports syndrome rapidly progressive gn rpgn membranoproliferative gn nephrotic. In this type of syndrome, there is a loss of a lot of blood and this is the most basic characterization of the syndrome. Difference between nephrotic syndrome and nephritic.
The blood protein albumin makes up much of the protein that is lost, though many other important proteins are also lost in nephrotic syndrome. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Nephritic syndrome is a clinical syndrome defined by the association of hematuria, proteinuria, and often arterial hypertension and renal failure. Generally, the prognosis of nephritic syndrome in children is better than it is in adults. Aug 21, 2015 while the incidence of nephrotic syndrome ns is decreasing in korea, the morbidity of difficulttotreat ns is significant.
Nephritic vs nephrotic syndrome keshav mudgal renal nephritic syndrome. Please subscribe my youtube channel and share my video. In the united states, diabetes mellitus is the most common cause of nephrotic syndrome. Nephrotic syndrome article about nephrotic syndrome by the. Nov 09, 2017 the classical nephritic syndrome has a sudden onset days weeks and the main cause is post streptococcal glomerulonephritis.
Difference between nephrotic and nephritic syndrome compare. Nephritic syndrome is characterized by glomerular damage leading to hematuria, pyuria, water retention, and. Nephrotic syndrome the signs and symptoms of nephritic and nephrotic syndrome are fairly similar, which is why it is quite difficult for affected individuals as well as healthcare professionals to correctly identify the ailment in the absence of medicallaboratory tests. Nephrotic range proteinuria is typically defined as greater than 3 to 3. Below is just a quick overview of which diseases are associated with which. Rapid and efficient diagnosis of diseases presenting as acute glomerulonephritis andor nephrotic syndrome is critical for early and appropriate therapy aimed at preservation of renal function. Patrick niaudet, in comprehensive pediatric nephrology, 2008. Common causes of nephritic syndrome are listed in table 4. Nephritic syndrome is a clinical syndrome defined by. Nephritic syndrome can present with oliguria, hypertension, and hematuria colacolored urine. Hodgkin disease, usually none nephrotic syndrome bun in 15 30% hla b8, b12 3.
Gland, pneumonia treatment, nephritis, nephrotic syndrome, and many others. Nephrotic syndrome after the application of mercury ointment. Edema may also be present, although it is not nearly as severe as in nephrotic syndrome. Nephritic syndrome clinical presentation, causes and.
Both nephritic syndrome and nephrotic syndrome are renal disorders which share few common symptoms. Nephrotic syndrome is a clinicopathological condition which develops when there is significant damage to the glomeruli which leads to heavy proteinuria 3. The thing with nephritic syndrome is that the lesions causing it all have increased cellularity within the glomeruli, accompanied by a leukocytic infiltrate hence the suffix itic. Nephritic syndrome knowledge for medical students and physicians. Most children up to 80% will go on to relapse several times proteinuria 3d with edema. This video is based on kidney disorder of nephrotic syndrome. Complications may include blood clots, infections, and high blood pressure causes include a number of kidney diseases such as focal segmental.
Nephrotic syndrome is a disease of the kidney while nephritic syndrome is a disease of the glomeruli. Nephrotic or nephritic syndrome can be caused by multiple disease processes. Diabetes mellitus is the most common cause of nephrotic syndrome in adults in the united states. Key difference glomerulonephritis vs nephrotic syndrome a syndrome is a combination of medical problems that show the existence of a particular disease or mental condition. However, there are differences between nephrotic syndrome and nephritic syndrome in the clinical features. Regardless of origin, the basic condition is characterized by hematuria, mild non nephrotic, ie less than 3. Low levels of protein in your blood hypoalbuminia swelling in your legs, feet, ankles, or hands edema sign up to download a protein guide and receive free lowprotein recipes. Laboratory findings include hematuria, proteinuria nephritic syndrome, there is some proteinuria and edema, but its not nearly as severe as in nephrotic syndrome. Nov 07, 20 nephrotic and nephritic syndromes are common childhood conditions presenting with oedema and proteinuria.
Pdf while the incidence of nephrotic syndrome ns is decreasing in korea, the morbidity of difficulttotreat ns is significant. On a superficial level, it is safe to say that nephritic syndrome is characterized by a loss of blood in the urine from the damaged renal epithelia, whereas in nephrotic syndrome, loss of proteins is very common in the urine analysis. Pathology relating to or affected with nephritis thesaurusantonymsrelated wordssynonymslegend. In these cases, the syndrome is called a primary, or idiopathic, nephrotic syndrome. Division of nephrology and hypertension powerpoint ppt presentation free to view acute renal failure acute renal failure deb goldstein argy resident september, 2005 acute renal failure rapid decline in the gfr over days to weeks. Nephrotic syndrome is characterized by severe proteinuria, i. Overview of nephritic syndrome genitourinary disorders. This is because each is associated with a particular subset of diseases. Nephritic syndrome an overview sciencedirect topics. It may occur in typical form, or in association with nephritic syndrome. Nephrotic vs nephritic syndrome faculty of medicine. One of the defining features used to determine the difference between nephritic and nephrotic syndromes is the amount of protein in the urine.
Nephrotic vs nephritic syndrome nephrotic and nephritic syndromes are common childhood conditions presenting with oedema and proteinuria. Nephritic vs nephrotic syndrome nursing nclex duration. Nephrotic syndrome poc nephritic syndrome edema hypoalbuminemia. Nephritic syndrome, like nephrotic syndrome, may involve hypoalbuminemia due to the protein albumin moving from the blood to the urine. Nephritic syndrome can develop rapidly acute glomerulonephritis or progress slowly. Children who have evidence of glomerular bleeding may have nephritic syndrome secondary to glomerulonephritis, and those with heavy proteinuria are likely to have nephrotic syndrome.
This includes protein in the urine, low blood albumin levels, high blood lipids, and significant swelling. This is video 1 of 1 on nephrotic vs nephritic syndromes. Rapidly progressive renal failure is a hall mark of rapidly progressive glomerulonephritis syndrome and presents with nephritic urine picture8. Nephritic syndrome is caused by inflammation of the glomerulus glomerlonephritis leading to proteinuria, hematuria. Nephrotic syndrome poc nephritic syndrome edema hypoalbuminemia proteinuria hypercholesterolemia not essential characteristic htn mild edema oliguria azotemia high jvp dark urine any inflammation cause proteinuria then edema then hypovolemia then more hypoalbuminemia and hyperlipidemia mechanism 2. The classical nephritic syndrome has a sudden onset days weeks and the main cause is post streptococcal glomerulonephritis. Treatment includes nonspecific measure aimed at controlling hypertension, edema, proteinuria and disease modifying immunosuppression. What is the difference between nephritic and nephrotic syndrome.
What is the difference between nephritic and nephrotic. Nephrotic syndrome vs nephritic syndrome explained nephritic vs. Jun 10, 2009 in nephritic syndrome, there is some proteinuria and edema, but its not nearly as severe as in nephrotic syndrome. The upcoming article will clear out difference via a table, differential diagnosis of the two syndromes and how to interpret reports to find out which one is. At the turn of the century, clinicians distinguished a nephritic syndrome of i. Overview of nephritic syndrome msd manual professional edition. Approximately onethird of patients with both type 1 and type 2 diabetes mellitus of at least a 25year duration will develop nephrotic syndrome, predictably leading to renal failure. The major determinant of whether the patient presents with gn and an active urine sediment nephritic syndrome or with proteinuria nephrotic syndrome and. Nephritic syndrome definition of nephritic syndrome by. Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. It is pretty easy to remember because nephrotic and protein both contains the alphabet o in the spellings. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. Nephritic syndrome is defined by hematuria, variable degrees of proteinuria, usually dysmorphic red blood cells rbcs, and often rbc casts on microscopic examination of urinary sediment. Relapses are treated with a 2nd course of steroids.
Nephritic syndrome is also known as glomerulonephritis and it is characterized by edema, increased blood pressure and haematuria red blood cells in urine. The clinical presentation of lupus nephritis is highly variable, ranging from asymptomatic hematuria andor proteinuria to frank nephritic syndrome to rapidly progressive glomerulonephritis with loss of renal function. Nephrotic syndrome poc nephritic syndrome edema hypo albuminemia. In a nephritic syndrome, all of these occur plus there is hematuria or blood in the urine. Nephritic syndrome is characterized by glomerular damage leading to hematuria, pyuria, water retention, and subsequent hypertension and edema. Nephritic definition of nephritic by the free dictionary. Urine samples are taken to diagnose people suspected of having nephrotic syndrome. Diagnosis and management charles kodner, md, university of louisville school of medicine, louisville, kentucky i n nephrotic syndrome, a variety of disorders cause. According to the cdc, nephritisnephrosis nephritic syndrome was the 9th leading cause of death in the united states in 2017. Glomerular diseases knowledge for medical students and. Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience. Nephrotic syndrome is more of protein proteinuria loss while the nephritic syndrome is more of blood loss hematuria.
Nephrotic syndrome is a condition involving the loss of significant volumes of protein via the kidneys proteinuria which results in. Age plays an important role in identifying the cause of nephritic syndrome. This article will talk about nephritic syndrome and nephrotic syndrome and the differences between them in detail highlighting their. The pathophysiology of glomerular diseases is complex. Start studying glomerulonephritis including nephrotic and nephritic syndromes.
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